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玉研仪器成立于2010年,坚持自主研发,致力于为客户提供生命科学研究和实验室建设有效、合理的系统解决方案
肺部液体给药器文献列表
2026
Vol. 12,1
Wang, Binghua, et al. "A softness zwitterionic micelles efficiently deliver inhaled nintedanib by enhancing airway mucus penetration." Science Advances 12.1 (2026): eady1030. DOI: 10.1126/sciadv.ady1030
2025
Vol. 2025
Huang, Keke, et al. "Topical delivery of a human single-domain antibody targeting IL-33 to inhibit mucosal inflammation." Cellular & Molecular Immunology (2025): 1-17. DOI:10.1038/s41423-025-01305-7
2025
Vol. 2025
Gao, Pengli, et al. "Cascade nanozyme of multi-antioxidant Mn-doped carbon dots counters cytokine storm in acute lung injury." Chemical Engineering Journal (2025): 168982. DOI:10.1016/j.cej.2025.168982
2025
Vol. 2025
Xu, Lin-Tao, et al. "Tussilagone attenuated cigarette smoke-induced chronic obstructive pulmonary disease through regulating Nrf2 and NF-κB/NLRP3 inflammasome via directly targeting cysteine 434 of KEAP1." Journal of Advanced Research (2025). DOI:10.1016/j.jare.2025.07.019
2025
Vol. 82
Yang, Kang, et al. "Sphaeropsidin A covalently binds to Cys 151 of Keap1 to attenuate LPS-induced acute pneumonia in mice." Redox Biology 82 (2025): 103621. DOI:10.1016/j.redox.2025.103621
2025
Vol. 2025
Zong, Yan, et al. "Intratracheal administration: Non-invasive approach for liver-targeted siRNA-LNP delivery." Nano Research (2025). DOI:10.26599/NR.2025.94908267
2025
Vol. 32,1
Wen, Zhiyang, et al. "Nebulized inhalation of novel baicalein liposome based on phospholipid complex to alleviate acute lung injury." Drug Delivery 32.1 (2025): 2596168.1454153. DOI:10.1080/10717544.2025.2596168
2025
Vol. 97,36
Xu, Yingying, et al. "Multifunctional Gold Nanoclusters for a Lung Tissue Distribution Study of a Novel Anti-asthma Inhaled Antibody." Analytical Chemistry 97.36 (2025): 19635-19653. DOI:10.1021/acs.analchem.5c03043
2025
Vol. 2025
Zhu, Xiaoshan, et al. "Size-Dependent Toxicity of Polystyrene Microplastics in Lung Cells: An in Vivo and in Vitro Study." Ecotoxicology and Environmental Safety (2025). DOI:10.1016/j.ecoenv.2025.119456
2025
Vol. 17,13
Bian, Yongning, et al. "Ionizable lipid nanoparticles enhance lung delivery of gold nanoclusters for improving acute lung injury alleviation." Nanoscale 17.13 (2025): 7888-7897. DOI:10.1039/D4NR05415F
2025
Vol. 16
Meng, Qinghe, et al. "Sparstolonin B nano-formulation attenuates LPS-induced lung injury." Frontiers in Pharmacology 16 (2025): 1532391. DOI:10.3389/fphar.2025.1532391
2025
Vol. 2025
Ma, Yuqing, et al. "Investigation of the material basis and mechanism of Qingfei Paidu granules in treating LPS-induced acute pneumonia using UPLC-Q-TOF-MS/MS, network pharmacology, molecular docking and experimental verification." Journal of Pharmaceutical and Biomedical Analysis (2025): 116973. DOI:10.1016/j.jpba.2025.116973
2025
Vol. 6
Qiu, Tao, et al. "Encapsulating extracellular vesicles with a minimal RISC complex as novel gene silencing tool." Extracellular Vesicle 6 (2025): 100094. DOI:10.1016/j.vesic.2025.100094
2025
Vol. 2025
Apalama, Marie Laurine, et al. "Aerosolized ApoA1 Nanoparticles Synthesized by Microfluidics Cross the Lung Barrier and Modulate Inflammation." bioRxiv (2025): 2025-07. DOI:10.1101/2025.07.09.663869
2025
Vol. 72,5
Lu, Peng, et al. "Circulating Mitochondrial N-Formyl Peptides Are Associated with Acute Respiratory Distress Syndrome after Cardiopulmonary Bypass and Regulate Endothelial Barrier through FPR2." American Journal of Respiratory Cell and Molecular Biology 72.5 (2025): 533-550. DOI: 10.1165/rcmb.2024-0076OC
2025
Vol. 2025
Zhang, Chenghao, et al. "Emodin nanocrystals enhanced mucus penetration and ameliorated bleomycin-induced pulmonary fibrosis by pulmonary delivery." Journal of Drug Targeting (2025): 1-11. DOI: 10.1080/1061186X.2025.2497369
2025
Vol. 2025
Yan, Jiahui, et al. "Effects of Simiao Pill on rheumatoid arthritis complicated with interstitial lung disease via the ATX/LPA/LPA1 and RhoA/ROCK2 signaling pathways." (2025). DOI: 10.21203/rs.3.rs-6597839/v1
2025
Vol. 99,5
Xu, Siqi, et al. "Identification and characterization of a broadly neutralizing and protective nanobody against the HA1 domain of H5 avian influenza virus hemagglutinin." Journal of Virology 99.5 (2025): e02090-24. DOI: 10.1128/jvi.02090-24
2024
Vol. 2024
Pan, Tingyu, et al. "Identification of potential mechanisms of Schisandrin B in the treatment of idiopathic pulmonary fibrosis by integrating network pharmacology and experimental validation." Naunyn-Schmiedeberg's Archives of Pharmacology (2024): 1-15. DOI: 10.1007/s00210-024-03605-7
2024
Vol. 71
Sun, Xiaolin, et al. "GSTP alleviates acute lung injury by S-glutathionylation of KEAP1 and subsequent activation of NRF2 pathway." Redox Biology 71 (2024): 103116. DOI: 10.1016/j.redox.2024.103116
2024
Vol. 62,2
Meng, Qinghe, et al. "Induced pluripotent stem cell-derived mesenchymal stem cells-derived extracellular vesicles attenuate LPS-induced lung injury and endotoxemia in mice." Shock 62.2 (2024): 294-303. DOI: 10.1097/SHK.0000000000002381
2024
Vol. 2024
Zhu, Chuanda, et al. "An elastase nanocomplex with metal cofactors for enhancement of target protein cleavage activity and synergistic antitumor effect." Chemical Engineering Journal (2024): 149902. DOI:10.1016/j.cej.2024.149902.
2024
Vol. 366
Han, Meng-Meng et al. “Inhaled nanoparticles for treating idiopathic pulmonary fibrosis by inhibiting honeycomb cyst and alveoli interstitium remodeling.” Journal of controlled release : official journal of the Controlled Release Society vol. 366 (2024): 732-745. DOI:10.1016/j.jconrel.2024.01.032
2024
Vol. 10,19
Zhang, Huizhe, et al. "Integrative analysis of the efficacy and pharmacological mechanism of Xuefu Zhuyu decoction in idiopathic pulmonary fibrosis via evidence-based medicine, bioinformatics, and experimental verification." Heliyon 10.19 (2024). DOI: 10.1016/j.heliyon.2024.e38122
2024
Vol. 2024
Yeshwante, Shekhar. "SYSTEMS-BASED APPROACH TO DESIGN AND OPTIMIZATION OF TREATMENT FOR PULMONARY INFECTIONS: STRATEGY TO COMBAT ANTIMICROBIAL RESISTANCE." (2024).
2023
Vol. 13
Chen, Huanjie, et al. "Enhanced secretion of hepatocyte growth factor in human umbilical cord mesenchymal stem cells ameliorates pulmonary fibrosis induced by bleomycin in rats." Frontiers in Pharmacology 13 (2023): 1070736. DOI: 10.3389/fphar.2022.1070736
2023
Vol. 12,3
Wang, Shuo, et al. "Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway." Translational Lung Cancer Research 12.3 (2023): 427. DOI: 10.21037/tlcr-22-675
2023
Vol. 59,6
Ma, Julia, et al. "Prophylactic nCMT-3 attenuates sepsis-induced acute kidney injury in association with NLRP3 inflammasome activation and apoptosis." Shock 59.6 (2023): 922-929. DOI: 10.1097/SHK.0000000000002118
2023
Vol. 309
Ba, Xin, et al. "Simiao pill attenuates collagen-induced arthritis and bleomycin-induced pulmonary fibrosis in mice by suppressing the JAK2/STAT3 and TGF-β/Smad2/3 signalling pathway." Journal of Ethnopharmacology 309 (2023): 116274. DOI: 10.1016/j.jep.2023.116274
2023
Vol. 13,15
Santin, Yohan, et al. "Inhalation of acidic nanoparticles prevents doxorubicin cardiotoxicity through improvement of lysosomal function." Theranostics 13.15 (2023): 5435. DOI: 10.7150/thno.86310
2023
Vol. 44,5
CHENG, Zhipeng, et al. "Therapeutic effect of perfluorocarbon aerosol inhalation on lung injury induced by seawater inhalation in rats." ACADEMIC JOURNAL OF CHINESE PLA MEDICAL SCHOOL 44.5 (2023): 508-513. DOI: 10.3969/j.issn.2095-5227.2023.05.012
2023
Vol. 9,2
Feng, Xin et al. “First magnetic particle imaging to assess pulmonary vascular leakage in vivo in the acutely injured and fibrotic lung.” Bioengineering & translational medicine vol. 9,2 e10626. 29 Nov. 2023. DOI:10.1002/btm2.10626
2023
Vol. 17,12
Liu, Chang et al. “An Inhalable Hybrid Biomimetic Nanoplatform for Sequential Drug Release and Remodeling Lung Immune Homeostasis in Acute Lung Injury Treatment.” ACS nano vol. 17,12 (2023): 11626-11644. DOI:10.1021/acsnano.3c02075
2023
Vol. 474
Yang, Guang, et al. "Noncovalent co-assembly of aminoglycoside antibiotics@ tannic acid nanoparticles for off-the-shelf treatment of pulmonary and cutaneous infections." Chemical Engineering Journal 474 (2023): 145703. DOI:10.1016/j.cej.2023.145703.
2023
Vol. 13,14
Sun, Han et al. “Application of Lung-Targeted Lipid Nanoparticle-delivered mRNA of soluble PD-L1 via SORT Technology in Acute Respiratory Distress Syndrome.” Theranostics vol. 13,14 4974-4992. 4 Sep. 2023, DOI:10.7150/thno.86466
2023
Vol. 171
Yue, Dayong et al. “Diesel exhaust PM2.5 greatly deteriorates fibrosis process in pre-existing pulmonary fibrosis via ferroptosis.” Environment international vol. 171 (2023): 107706. DOI:10.1016/j.envint.2022.107706
2023
Vol. 35,1
Lin, Wei-Ting et al. “Modulation of experimental acute lung injury by exosomal miR-7704 from mesenchymal stromal cells acts through M2 macrophage polarization.” Molecular therapy. Nucleic acids vol. 35,1 102102. 14 Dec. 2023. DOI:10.1016/j.omtn.2023.102102
2023
Vol. 180,24
Xiao, Xue et al. “SerpinB1 is required for Rev-erbα-mediated protection against acute lung injury induced by lipopolysaccharide-in mice.” British journal of pharmacology vol. 180,24 (2023): 3234-3253. DOI:10.1111/bph.16175
2023
Vol. 30,1
Xu, Yingying et al. “PEGylated pH-responsive peptide-mRNA nano self-assemblies enhance the pulmonary delivery efficiency and safety of aerosolized mRNA.” Drug delivery vol. 30,1 (2023): 2219870. DOI:10.1080/10717544.2023.2219870
2023
Vol. 49,1
Chen, Ping et al. “Chronic exposure to ampicillin alters lung microbial composition in laboratory rat.” Experimental lung research vol. 49,1 (2023): 116-130. DOI:10.1080/01902148.2023.2219790
2022
Vol. 2022
Zhang, Huizhe, et al. "Danggui buxue decoction ameliorates idiopathic pulmonary fibrosis through MicroRNA and messenger RNA regulatory network." Evidence‐Based Complementary and Alternative Medicine 2022.1 (2022): 3439656. DOI: 10.1155/2022/3439656
2022
Vol. 185,8
Li, Cheng et al. “Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody.” Cell vol. 185,8 (2022): 1389-1401.e18. DOI:10.1016/j.cell.2022.03.009
2022
Vol. 11,4
Peng, Boya et al. “Robust delivery of RIG-I agonists using extracellular vesicles for anti-cancer immunotherapy.” Journal of extracellular vesicles vol. 11,4 (2022): e12187. DOI:10.1002/jev2.12187
2022
Vol. 352
Zhang, Mengjun et al. “Airway epithelial cell-specific delivery of lipid nanoparticles loading siRNA for asthma treatment.” Journal of controlled release : official journal of the Controlled Release Society vol. 352 (2022): 422-437. DOI:10.1016/j.jconrel.2022.10.020
2022
Vol. 13
Han, Meishan et al. “Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis.” Frontiers in pharmacology vol. 13 882678. 25 Apr. 2022. DOI:10.3389/fphar.2022.882678
2022
Vol. 72
Cai, Zimin, et al. "Enhanced protective activity of 1, 8-cineole on emphysema using hyaluronic acid-coated liposomes via quantitative pulmonary administration in mice." Journal of Drug Delivery Science and Technology 72 (2022): 103402. DOI:10.1016/j.jddst.2022.103402
2022
Vol. 27,11
Peng, Jianqing et al. “Carboxymethyl Chitosan Modified Oxymatrine Liposomes for the Alleviation of Emphysema in Mice via Pulmonary Administration.” Molecules (Basel, Switzerland) vol. 27,11 3610. 4 Jun. 2022. DOI:10.3390/molecules27113610
2022
Vol. 57,5
Meng, Qinghe et al. “Nano-chemically Modified Tetracycline-3 (nCMT-3) Attenuates Acute Lung Injury via Blocking sTREM-1 Release and NLRP3 Inflammasome Activation.” Shock (Augusta, Ga.) vol. 57,5 (2022): 749-758. DOI:10.1097/SHK.0000000000001927
2021
Vol. 11,8
Gu, Peiyu et al. “Protective function of interleukin-22 in pulmonary fibrosis.” Clinical and translational medicine vol. 11,8 (2021): e509. DOI:10.1002/ctm2.509
2021
Vol. 13,3
Wu, Lan et al. “Poly(lactide-co-glycolide) Nanoparticles Mediate Sustained Gene Silencing and Improved Biocompatibility of siRNA Delivery Systems in Mouse Lungs after Pulmonary Administration.” ACS applied materials & interfaces vol. 13,3 (2021): 3722-3737. DOI:10.1021/acsami.0c21259
2021
Vol. 13,48
Tian, Xidong et al. “Pulmonary Delivery of Reactive Oxygen Species/Glutathione-Responsive Paclitaxel Dimeric Nanoparticles Improved Therapeutic Indices against Metastatic Lung Cancer.” ACS applied materials & interfaces vol. 13,48 (2021): 56858-56872. DOI:10.1021/acsami.1c16351
2021
Vol. 139
Yang, Huilin et al. “Triptolide dose-dependently improves LPS-induced alveolar hypercoagulation and fibrinolysis inhibition through NF-κB inactivation in ARDS mice.” Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol. 139 (2021): 111569. DOI:10.1016/j.biopha.2021.111569
2021
Vol. 9,13
Su, Ruonan et al. “Venetoclax nanomedicine alleviates acute lung injury via increasing neutrophil apoptosis.” Biomaterials science vol. 9,13 (2021): 4746-4754. DOI:10.1039/d1bm00481f
2020
Vol. 173,2
Wang, Ping, et al. "Effect of intratracheal instillation of ZnO nanoparticles on acute lung inflammation induced by lipopolysaccharides in mice." Toxicological Sciences 173.2 (2020): 373-386. DOI: 10.1093/toxsci/kfz234
2020
Vol. 21,1
Wu, Yanqi et al. “SN50 attenuates alveolar hypercoagulation and fibrinolysis inhibition in acute respiratory distress syndrome mice through inhibiting NF-κB p65 translocation.” Respiratory research vol. 21,1 130. 27 May. 2020。DOI:10.1186/s12931-020-01372-6
2020
Vol. 152
Wu, Lan, et al. "Quantitative comparison of three widely-used pulmonary administration methods in vivo with radiolabeled inhalable nanoparticles." European Journal of Pharmaceutics and Biopharmaceutics 152 (2020): 108-115. DOI:10.1016/j.ejpb.2020.05.004